RASGRP3 (Human) Recombinant Protein (Q02)
产品名称: RASGRP3 (Human) Recombinant Protein (Q02)
英文名称: RASGRP3 (Human) Recombinant Protein (Q02)
产品编号: H00025780-Q02
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
                            亚诺法生技股份有限公司(Abnova)
                            
                                
                            
                        
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 - 邮编 : 11493
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 - 邮箱 : sales@abnova.com.tw
 
- Specification
 
- Product Description:
 - Human RASGRP3 partial ORF ( NP_733772.1, 1 a.a. - 99 a.a.) recombinant protein with GST-tag at N-terminal.
 
- Sequence:
 - MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYRNATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMT
 
- Theoretical MW (kDa):
 - 36.63
 
- Preparation Method:
 - in vitro wheat germ expression system
 
- Purification:
 - Glutathione Sepharose 4 Fast Flow
 
- Storage Buffer:
 - 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
 
- Storage Instruction:
 - Store at -80°C. Aliquot to avoid repeated freezing and thawing.
 
- Quality Control Testing:
 - 12.5% SDS-PAGE Stained with Coomassie Blue.

 
- Note:
 - Best use within three months from the date of receipt of this protein.
 
- MSDS:
 
Download
- Application Image
 
- Enzyme-linked Immunoabsorbent Assay
 
- Western Blot (Recombinant protein)
 
- Antibody Production
 
- Protein Array
 
- Entrez GeneID:
 - 25780
 
- GeneBank Accession#:
 - NM_170672
 
- Protein Accession#:
 - NP_733772.1
 
- Gene Name:
 - RASGRP3
 
- Gene Alias:
 - GRP3,KIAA0846
 
- Gene Description:
 - RAS guanyl releasing protein 3 (calcium and DAG-regulated)
 
- Omim ID:
 - 609531
 
- Gene Ontology:
 - Hyperlink
 
- Gene Summary:
 - Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM
 
- Other Designations:
 - guanine nucleotide exchange factor for Rap1
 
